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Polar compounds isolated from the leaves of Albertisia delagoensis (Menispermaceae)

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dc.contributor.author Hawkes, Geoffrey E.
dc.contributor.author de Wet, Helene
dc.contributor.author Li, Jia
dc.date.accessioned 2017-12-19T12:32:42Z
dc.date.available 2017-12-19T12:32:42Z
dc.date.copyright 2011
dc.date.created 2017
dc.date.issued 2011
dc.identifier.issn 1420-3049
dc.identifier.uri http://hdl.handle.net/10907/1603
dc.description.abstract Aqueous infusions of the leaves of the shrub Albertisia delagoensis (Menispermaceae) are used in South Africa in traditional Zulu medicine to alleviate a variety of symptoms, including fever, and intestinal problems. We report the analysis of such an aqueous extract using the HPLC-NMR technique. A number of polar compounds were identified, including proto-quercitol, nicotinic acid, allantoic acid, 3,4-dihydroxybenzoic acid, phthalic acid and the aporphine alkaloid derivative roemrefidine. Allantoic acid and roemrefidine have been fully characterised by 1H- and 13C-NMR and mass spectrometry. Earlier reports of antiplasmodial activity of roemrefidine and of A. delagoensis extracts are correlated with this study and with the antipyretic properties of neutral aqueous extracts. en_US
dc.description.sponsorship National Research Foundation en_US
dc.format.extent Molecules 2011, 16, 9153-9160 en_US
dc.format.medium pdf en_US
dc.language.iso en en_US
dc.publisher www.mdpi.com/journal/molecules en_US
dc.relation.requires Adobe Acrobat Reader en_US
dc.relation.uri doi:10.3390/molecules16119153 en_US
dc.rights National Research Foundation en_US
dc.subject Albertisia delagoensis en_US
dc.subject traditional medicine en_US
dc.subject roemrefidine en_US
dc.subject allantoic acid en_US
dc.subject HPLC-NMR en_US
dc.title Polar compounds isolated from the leaves of Albertisia delagoensis (Menispermaceae) en_US
dc.type Article en_US
dc.rights.holder © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). en_US


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